The spatial organization of sphingofungin biosynthesis in Aspergillus fumigatus and its cross-interaction with sphingolipid metabolism
ABSTRACT Sphingofungins are Lid Lock Assembly sphinganine analog mycotoxins acting as inhibitors of serine palmitoyl transferases, enzymes responsible for the first step in the sphingolipid biosynthesis.Eukaryotic cells are highly organized with various structures and organelles to facilitate cellular processes and chemical reactions, including the